Mistacor AM Dosage/Direction for Use

Adults: Telmisartan + Amlodipine besilate should be taken once daily.
Replacement therapy: Patients receiving telmisartan and amlodipine besilate from separate tablets can instead receive Telmisartan + Amlodipine besilate containing the same component doses in one tablet once daily, e.g. to enhance convenience or compliance.
Add on therapy: Telmisartan + Amlodipine besilate may be administered in patients whose blood pressure is not adequately controlled with amlodipine or telmisartan alone. Patients treated with 10 mg amlodipine who experience any dose limiting adverse reactions such as oedema, may be switched to Telmisartan + Amlodipine besilate 40 mg/5 mg once daily, reducing the dose of amlodipine without reducing the overall expected antihypertensive response.
Initial therapy: A patient may be initiated on Telmisartan + Amlodipine besilate if it is unlikely that control of blood pressure would be achieved with a single agent. The usual starting dose of Telmisartan + Amlodipine besilate is 40 mg/5 mg once daily.
Patients requiring larger blood pressure reductions may be started on Telmisartan + Amlodipine besilate 80 mg/5 mg once daily.
If additional blood pressure lowering is needed after at least 2 weeks of therapy, the dose may be titrated up to a maximum of 80 mg /10 mg once daily.
Telmisartan + Amlodipine besilate can be administered with other antihypertensive drugs.
Special populations: Renal impairment: No posology adjustment is required for patients with renal impairment, including those on hemodialy­sis. Telmisartan + Amlodipine are not dialyzable.
Hepatic impairment: In patients with mild to moderate hepatic impairment, Telmisartan + Amlodipine besilate should be administered with caution. For telmisartan, the posology should not exceed 40 mg once daily.
Elderly: No dose adjustment is necessary for elderly patients.
Pediatric population: Telmisartan + Amlodipine besilate is not recommended for use in patients aged below 18 years due to a lack of data on safety and efficacy.
Method of Administration: Tablet for oral administration: Telmisartan + Amlodipine besilate may be taken with or without food.
Or as prescribed by the physician.